The Endocannabinoid System

 

The endocannabinoid system (ECS) is made up of a collection of cell receptors and corresponding molecules. You can think of cell receptors like little locks on the surface of your cells. The keys to these locks are called endocannabinoids.

Endocannabinoids are the chemical messengers that tell your body when to get processes moving and when to stop. Each time an endocannabinoid binds to a cell, it relays a message, giving your cell specific direction.

Certain receptors are more concentrated in specific regions. CB1 receptors are abundant in the central nervous system. CB2 receptors are more often found on immune cells, in the gastrointestinal tract and in the peripheral nervous system. The diversity of receptor locations shows just how important endocannabinoids are for day-to-day bodily function.

The ECS helps to maintain optimal balance in the body – known as homeostasis. It also helps regulate sleep, appetite, digestion, hunger, mood, motor control, immune function, reproduction and fertility, pleasure and reward, pain, memory and temperature regulation.

When the ECS is disrupted, any one of these things can fall out of balance. When the body does not produce enough endocannabinoids or cannot regulate them properly, you are more susceptible to illnesses that affect one or several of the functions mentioned above.

The endocannabinoid system is extremely complex and plays important roles in many vital processes, and it holds promise as a treatment target for many debilitating conditions.

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ananda professional full spectrum hemp extract

Ananda Professional : Frequently Asked Questions

  • Are hemp and marijuana the same?
    • No. Hemp is completely different from marijuana in its function, cultivation and application. Marijuana, as it is widely known, is used for medicinal or recreational purposes. Hemp is used in a variety of other applications that marijuana couldn’t possibly be used in. These include healthy dietary supplements, skin products, clothing and accessories.

      Marijuana contains many chemical compounds that create the different characteristics of the plant. Terpenes provide flavors and aromas, while chlorophyll in the leaves makes the plant green – but the most important chemicals in marijuana are the cannabinoids.

  • Are your products legal?
    • Yes. Our products are grown in Kentucky – the state that legalized the commercial growing of industrial hemp. We work closely with the State of Kentucky and the Department of Agriculture to ensure we are compliant with all existing laws regarding hemp extracts and byproducts.

      Section 7606 of the federal law states that regardless of another federal law (including the Controlled Substances Act), if the growing and cultivation of industrial hemp is allowed under state law and overseen by the Department of Agriculture, then the product can be manufactured and sold as part of the state’s approved hemp pilot program.

  • How do I get patients started?
      • Cannabinoids, particularly CBD, demonstrate a bell-shaped dose-response curve; therefore, it is imperative that patients slowly titrate up to their optimal dose without going over.
      • To find an optimal dose, patients should eliminate the use of any cannabis product for two days. Going over the optimal dose could cause the patient to lose the maximum benefits.
      • Most patients prefer to start using CBD about two hours before bedtime. Patients should start with 10-15mg of active cannabinoids once daily, increasing the dose slowly every 2-3 days to determine if a better therapeutic effect results.
        • For example, use 10mg once daily for two days, then increase to 10mg twice daily (morning and night) for two days.
        • Continue to slowly titrate the dose up every few days.
        • Once a point is reached where the therapeutic benefits do not increase OR where they decrease, stop and go back to the previous dose. This is the top of that individual’s bell-shaped dose-response curve.
  • What are cannabinoids?
    • Cannabinoids are the chemicals that give the cannabis plant its medical and recreational properties. Among the 113 cannabinoids produced, THC and CBD are the most prevalent and the most well-understood. Most strains of marijuana sold today are cultivated with higher levels of THC.

      THC is known for its psychoactive properties and is the reason you feel “high” after ingesting marijuana.

      CBD is a non-psychoactive cannabinoid and actually works to counteract the high. CBD also has numerous benefits, such as anti-inflammatory and neuroprotective properties.

      Whether produced by the body or in a plant, these naturally-occurring compounds all interact with the endocannabinoid system.

  • What is the endocannabinoid system?
    • The endocannabinoid system refers to a collection of cell receptors and corresponding molecules. You can think of cell receptors like little locks on the surface of your cells. The keys to these locks are called endocannabinoids. Each time an endocannabinoid binds to a cell it relays a message, giving your cell-specific direction.

      There are two different types of cannabinoid receptors: CB1 and CB2. CB1 receptors are found primarily in the brain and responsible for the psychoactive effects of marijuana. Each time an endocannabinoid binds to a cell, it relays a message, giving your cell specific direction.

  • What is the entourage effect, and why is it important?
    • Cannabinoids, terpenes and other chemical compounds found in cannabis achieve limited success when working in isolation or as individual components. Research suggests that when these individual components of the cannabis plant support one another, therapeutic benefits are magnified. Together, they produce an effect that is greater than the sum of their parts. This phenomenon is known as the “entourage effect.” The entourage effect supports the idea that whole plant medicine is superior to pure extracts.

  • WILL I GET HIGH FROM HEMP?
    • No. While there are at least 113 known cannabinoids produced by the hemp plant, cannabis is identified by its two active ingredients: THC and CBD. THC is the only molecule in the cannabis family with a psychoactive component. It’s the only one that will get you “high.” CBD, even at extremely high doses, will not make you feel “high.”

      There are hundreds of other cannabinoids, terpenes and phytonutrients present in the cannabis plant that are beneficial to overall health and wellness; unfortunately, they are improperly associated with the properties of one molecule, THC.

      Section 7606 of the Farm Bill defines industrial hemp as cannabis plants with <0.3% THC. Our products contain a full spectrum of cannabinoids, including THC and CBD. To maintain compliance with all laws, our products are rigorously tested to ensure a level of <0.3% THC.